Automating the Valita Titer Assay

The Valita Titer assay easily integrates into automated workflows to provide a fully automated IgG quantification platform. It’s compatible with most platforms, including our Biomek i-Series Automated Workstations.

 

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The addition of automation into your experimental workflows can help increase throughput and improve the reproducibility and reliability of data. It can also free up a significant amount of time and gives you the freedom to walk away from experiments and take care of other tasks on your to-do list.

Automation in Action

In this application note, we present the Valita Titer assay combined with a Biomek i5 automated liquid handler and Molecular Devices SpectraMax® iD5 Multi-Mode Microplate Reader.

Automated Screening Platform for IgG Quantification

This specific integration enabled the quantification of up to 456 samples (5 x 96-well plates) in a little over an hour with the presentation of a direct output of IgG titer results.

Two other experiments were performed as part of this work to:

  1. Demonstrate the ability of this workflow to accurately quantitate IgG in the presence of Chinese Hamster Ovary (CHO) cells
  2. Demonstrate the utilization of dilution factors to expand the assay range simply by inputting desired acquisition settings to the Biomek CLD protocol

Read the Application Note

Insightful Resources


 
Application Note
A High-Throughput, Automated Screening Platform for IgG Quantification During Drug Discovery and Development

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Brochure
Valita Titer IgG Quantification Assay
Brochure

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Learn More About the Valita Titer Assay

Introducing Valita Titer Assays

Valita Titer plate-based, 96- and 384-well assays that offer a rapid, cost-effective way to measure IgG

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Compare IgG Measurement Technologies

See how the Valita Titer assay compares to Protein A HPLC, ELISA and biolayer interferometry

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Say Goodbye to Sample Preparation

Measure IgG titer straight from cell culture samples—no sample prep, additional reagents or wash required

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valita titer webinar FAST SELECTION OF HIGH-PRODUCING CHOEXPRESS® CLONES USING VALITA TITER

Cell Line Development Webinar

Speed up your clone selection process with the Valita Titer assay

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Let’s Accelerate Your Antibody Discovery and Development

Interested in a demo? Just want to ask a few questions?
We’re here to help, please reach out anytime.

 

© For Research Use Only. Not for use in diagnostic procedures. Valita, Valita Titer and the ValitaCell logo are trademarks or registered trademarks of ValitaCell Ltd in the United States and other countries. ValitaCell is a Beckman Coulter Company.

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NOT ALL PRODUCTS ARE AVAILABLE IN ALL COUNTRIES. PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS The listed regulatory status for products correspond to one of the below: IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use." ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagent. Analytical and performance characteristics are not established." CE-IVD, CE: Products intended for in vitro diagnostic use and conforming to the In Vitro Diagnostic Regulation (IVDR) (EU) 2017/746. (Note: Devices may be CE marked to other directives.) RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures." LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only." No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.