Simplifying Analysis with the Valita Titer Assay

An analytical development group in the biopharma industry is a team of scientists and researchers dedicated to developing, optimizing and running methods and techniques for the analysis of biological samples and compounds. This group focuses on designing, validating, and implementing analytical assays and technologies as an internal service. This supports various aspects of drug development and manufacturing such as the characterization of critical quality attributes (CQA) of specific drugs.

Analytical development groups can use the Valita Titer Assay at various stages of their workflow to determine the concentration or titer of IgG antibodies.

 

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Rapid & High-Throughput IgG Quantification

The Valita Titer Assay enhances the antibody process development workflow by enabling rapid, high-throughput IgG quantification directly from crude cell culture sample. It supports the early-stage evaluation, optimization of culture conditions, scale-up/down assessment, process robustness evaluation, and troubleshooting. 

 

Rapid and High-Throughput Analysis
The Valita Titer Assay allows you to improve your analytics turnaround time and make informed decisions faster.

 

Enhanced Sensitivity and Specificity
The Valita Titer Assay provides high sensitivity and specificity in quantifying IgG. This assay requires a minimal sample volume, while maximizing the information you can obtain from each and optimizing the resource utilization.

 

Simplified Analytics
The Valita Titer Assay offers a streamlined workflow that simplifies your analytical processes. With its simple add-mix-read workflow, it minimizes the complexity associated with antibody titer quantification and eliminates the need for sample preparation or wash.

 

 

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The Power of Fluorescence Polarization

Thanks in part to the power of fluorescence polarization, the Valita Titer Assay is among the fastest, easiest and readily-automatable quantification assays available.

Fluorescence polarization is a widely used technique for monitoring binding events in solution. It’s based on the observation that when a fluorescently labeled molecule is excited with plane-polarized light, it emits light with a level of polarization that is inversely proportional to the rate of molecular rotation. 

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